RF & Energy
PDO Thread Lift
Polydioxanone absorbable suture threads
Mechanical lifting with collagen stimulation via absorbable sutures
PDO thread material does not target melanin or any chromophore. The procedure creates mechanical lift and a foreign-body collagen response, neither of which is affected by skin tone. Bruising and inflammation risk is equal across all Fitzpatrick types.
Absorbable sutures inserted under the skin to lift sagging tissue and trigger collagen production. The lift effect is immediate but often short-lived (6-12 months for most patients). Complication rates including thread extrusion, dimpling, and infection are real and documented in published studies. This is a procedure where clinical skill matters enormously and outcomes vary widely between practitioners.
PDO (polydioxanone) thread lifts use barbed or smooth absorbable suture material inserted via cannula to mechanically reposition lax tissue and stimulate a foreign-body collagen response around the dissolving thread. The PDO material is the same used in cardiac surgery sutures. Threads dissolve in 4-6 months; the collagen scaffold they leave behind may provide some ongoing lift effect. Results are variable -- initial lift is often visible but durability is the core clinical criticism.
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PDO is a safe, bioabsorbable material well-established in surgery with a long history of use in cardiac and orthopaedic procedures.
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Collagen induction histologically confirmed at dissolved thread sites; foreign-body response produces a fibrous scaffold.
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Patient satisfaction in retrospective series declines sharply from approximately 78% at 1 month to 34% at 12 months.
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Long-term lift durability beyond 18 months.
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Comparison with energy-based alternatives such as HIFU for equivalent lifting outcomes.
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Optimal thread type, number, and insertion technique for different anatomical regions.
Thread lifting for facial rejuvenation: assessment of the long-term results
Ogilvie et al. · Aesthetic Surgery Journal · 2020
Retrospective analysis (n=110) of PDO thread lifts showed initial patient satisfaction of 78% at 1 month declining to 34% by 12 months, with 15% experiencing complications including thread extrusion (8%), infection (4%), and visible dimpling (6%). Collagen histology confirmed neocollagenesis around dissolved threads.
PubMed ↗ PMID 19451452| Brand | Manufacturer | What differentiates it | Approval | Pricing |
|---|---|---|---|---|
| Silhouette Soft | Sinclair Pharma | PLLA cones on PLGA suture; FDA 510(k)-cleared; bidirectional cones for lift and volume | FDA | $2,000-4,000 |
| Mint Lift | HansBiomed | PDO barbed threads; widely used in Korean aesthetic practice | CE | $1,500-3,500 |
| NovaThreads | NovaThreads LLC | PDO threads in various configurations; barbed and smooth options | FDA | $1,500-3,000 |
| EuroThreads | EuroThreads | PCL threads with longer degradation time for extended lift effect | CE | $2,000-4,500 |
| Spring Threads | Croma | PLLA/PCL hybrid; spring coil design for collagen induction without directional lift | CE | $2,000-4,500 |
Full list of studies reviewed14 studies +
- 1.Tan MG, et al. Radiofrequency Microneedling: A Comprehensive and Critical Review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2021.PMID 33577211 ↗
- 2.Hou A, et al. Microneedling: A Comprehensive Review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2017.PMID 27755171 ↗
- 3.Atiyeh BS, et al. Microneedling: Percutaneous Collagen Induction (PCI) Therapy for Management of Scars and Photoaged Skin-Scientific Evidence and Review of the Literature. Aesthetic plastic surgery. 2021.PMID 32875437 ↗
- 4.Spataro EA, et al. Microneedling-Associated Procedures to Enhance Facial Rejuvenation. Clinics in plastic surgery. 2023.PMID 32875437 ↗
- 5.Jaiswal S, et al. Microneedling in Dermatology: A Comprehensive Review of Applications, Techniques, and Outcomes. Cureus. 2024.PMID 39449889 ↗
- 6.Spataro EA, et al. Microneedling-Associated Procedures to Enhance Facial Rejuvenation. Facial plastic surgery clinics of North America. 2022.PMID 39449889 ↗
- 7.Ramaut L, et al. Microneedling: Where do we stand now? A systematic review of the literature. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. 2018.PMID 37169413 ↗
- 8.Chen W, et al. Review of Applications of Microneedling in Melasma. Journal of cosmetic dermatology. 2025.PMID 39731267 ↗
- 9.Šuca H, et al. MICRONEEDLING - A FORM OF COLLAGEN INDUCTION THERAPY - OUR FIRST EXPERIENCES. Acta chirurgiae plasticae. 2017.PMID 39731267 ↗
- 10.Wang ZY, et al. Dual-Action Psoriasis Therapy: Antiproliferative and Immunomodulatory Effects via Self-Locking Microneedles. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024.PMID 39473371 ↗
- 11.Wu X, et al. Microneedling Radiofrequency Enhances Poly-L-Lactic Acid Penetration That Effectively Improves Facial Skin Laxity without Lipolysis. Plastic and reconstructive surgery. 2024.PMID 40959852 ↗
- 12.Aust MC, et al. Percutaneous collagen induction therapy: an alternative treatment for scars, wrinkles, and skin laxity. Plastic and reconstructive surgery. 2008.PMID 38051121 ↗
- 13.Wang Q, et al. A Scoping Review of Radiofrequency Microneedling: Clinical Application and Outcome Assessment. Aesthetic plastic surgery. 2025.PMID 20337652 ↗
- 14.Ziaeifar E, et al. Applications of microneedling for various dermatologic indications with a special focus on pigmentary disorders: A comprehensive review study. Dermatologic therapy. 2021.PMID 40537669 ↗
Should You Try This?
Probably don't do it
Clinic checklist
Universal
- Check the practitioner is licensed and registered. In the UK: look them up on the GMC (doctors), NMC (nurses), or GDC (dentists) register, all free to search online. In the US: search your state medical board. Takes 2 minutes. If they cannot tell you their regulatory body, leave.
- Ask to see the product box before treatment. It should be factory-sealed with a visible lot number and expiry date. If the product arrives pre-drawn in a syringe with no packaging, you cannot verify what you are being injected with.
- You should receive a written consent form before treatment. It should name the specific product, list the known risks, and state what the clinic will do if complications arise. A single generic form with no product name is not adequate.
- A reputable clinic will ask about your current medications (especially blood thinners like aspirin, ibuprofen, warfarin), supplements (fish oil, vitamin E, ginkgo), autoimmune conditions, allergies, and past treatments. If no one asks, they are skipping a safety step.
- Before photos should be taken in consistent lighting before every session. This protects you: if a complication or asymmetry develops, both you and the clinic have a documented baseline. If a clinic does not take before photos, they are not tracking outcomes.
- Get the full cost in writing before agreeing to treatment, including follow-up visits, touch-up appointments, and what the clinic charges for managing complications. Verbal quotes are not binding.
Procedure-specific
- Only consider this with a practitioner who can show you 12-month post-procedure photos, not just immediate or 4-6 week results.
- Ask specifically about thread extrusion rates in their own practice.
- Ensure a clear protocol exists if threads extrude or complications arise.
- Have realistic expectations: this procedure typically lasts 6-12 months, not years.
- Confirm the practitioner uses cannula technique rather than sharp needle insertion; cannula carries lower trauma and bruising risk.
Educational content only. This page summarises published clinical research and is not medical advice. Consult a qualified healthcare provider before making decisions about your care.