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Alpha Arbutin

Alpha-arbutin (4-hydroxyphenyl alpha-D-glucopyranoside)

Tyrosinase inhibitor for brightening without hydroquinone risks

HyperpigmentationDark Spots
Top-rated products

Sourced via EWG Skin Deep, one of the scientific databases used by the Yuka app to evaluate cosmetic ingredient safety.

Alpha Arbutin 2% + HA

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Key Study

Nano-vesicular systems for melanocytes targeting and melasma treatment: In-vitro characterization, ex-vivo skin retention, and preliminary clinical appraisal

Hatem S et al. · International Journal of Pharmaceutics · 2024

Nano-vesicular alpha-arbutin formulations showed superior melanocyte targeting and skin depigmenting efficacy in clinical testing.

PubMed ↗  PMID 39306205
Quick Facts
DurationTwice daily; visible brightening in 6-12 weeks
Studies2+
FDA StatusOTC cosmetic ingredient
Price$8-$30

Full briefing coming soon.

Should You Try This?

15108OUT OF 10

Probably okay to try

Educational content only. This page summarises published clinical research and is not medical advice. Consult a qualified healthcare provider before making decisions about your care.

Researched by

Val Yermakova

Informed Girl · informedgirl.com